Friday, October 16, 2015

Familiar with Early-Onset Neutropenia in a Small for Gestational Age Infant? After Reading a New Study You Will Be!

By: Lewis First, MD, MS; Editor-in-Chief      

        Small for gestational age (SGA) infants are known to have early neutropenia when compared to normal size infants at a gestational age—but just what do we know about this neutropenia?  How common is it? How long does it last?  What might be causing it and what makes it better?  
       These questions and more are answered in an informative study by Christensen et al. (doi: 10.1542/peds.2015-1638) being released this month in our journal who looked at ten years of neutropenia in the first week of life in more than 200 SGA infants out of 3600 studied compared to less than 50 out of 3650 non-SGA infants.  The authors looked at a variety of factors associated or not-associated with this neutropenia ranging from necrotizing enterocolitis to thrombocytopenia and give us a much clearer picture of what the “neutropenia of SGA” is all about.  
        If you want to know more about a common finding in your SGA newborns and what to follow and worry about (or not) in this neutropenic population, then reading this study should be an easy “cell.”

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