Wednesday, April 1, 2015

Antibiotic Usage in Infancy and Being Overweight: Weighing in on an Unexpected Association


By: Lewis First, MD, MS; Editor-in-Chief  
     How often have you considered that antibiotics given in infancy might predispose your patient to being overweight by age 2 years?  We certainly did not until we read the study by Saari et al. (doi: 10.1542/peds.2014-3407) and realized that the intestinal microbiome might be the culprit responsible for such an association. 
     The authors studied a population-based cohort of approximately 6 thousand boys and a similar number of girls in the first 24 months of life and looked at antibiotic purchase data as well as body mass index and height at 2 years of age. Since antibiotics can change the human microbiome, especially in infancy, doing so may trigger additional weight gain. 
      Why this happens is the subject of a provocative discussion section of this study, making this article well worth your attention. 

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1 comment:

  1. Very Interesting Post. Ich habe darüber fragen und über deine so dass es verständlich ist, geschrieben. Danke.
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