Tuesday, April 28, 2015

Another Study Heralds Early Benefits of HPV Vaccine in Preventing Cervical Dysplasia and Anogenital Warts

By: Lewis First, MD, MS; Editor-in-Chief    

          Our journal, like others, has published a number of studies demonstrating the benefits of human papillomavirus (HPV) vaccine but there is minimal information published about the effectiveness of the vaccine using a large population-based cohort, that is until this week when we share the results of a large study by Smith et al. (doi: 10.1542/peds.2014-2961) of eighth grade girls in Ontario, Canada before and after an eighth grade vaccination program was instituted.   
     The authors chose to look at absolute risk differences, relative risks, and the 95% confidence intervals attributable to vaccination in girls eligible for this program and then examined these girls again in grades 10-12 for cervical dysplasia and anogenital warts comparing them to those who were unvaccinated.  The results are impressive and demonstrate strong evidence of the benefits of early vaccination against HPV. 
       If you need nice proof that the HPV vaccine can make a difference—check this study out and then share it with your teen patients and their parents who might be hesitant to consent to getting this important vaccine.


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