Friday, December 5, 2014

Is There an Association between Caesarean Section and Chronic Immune Disorder Development?


USAF photo by Tech. Sgt. Suzanne M. Day
By: Lewis First, MD, MS; Editor-in-Chief 

Sometimes we receive manuscripts that point out associations we have never before considered—and this week one such study is being published in our journal regarding the association between the increased rate of caesarean sections and the increased prevalence of chronic immune diseases like asthma, allergy, inflammatory bowel disease and type-1 diabetes.

Bisgaard et al. (doi:10.1542/peds.2014-0596) studied more than 2 million term children in a Danish registry from time of birth over 35 years and tracked them for hospitalization for chronic immune diseases such as those just mentioned above.

Controlling for confounders, the authors found that children delivered by caesarean section had an increased association with a variety of chronic immune diseases but not all of them (e.g., type-1 diabetes, psoriasis or celiac disease).

Just what role a caesarean section might play in association with an increased risk of a chronic immune disease is the basis for an interesting discussion section in this study—and you should not be immune to reading it to learn more. 

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