By: Lewis First, MD, MS; Editor-in-Chief
How often have you considered that antibiotics given in infancy might predispose your patient to being overweight by age 2 years? We certainly did not until we read the study by Saari et al. (doi: 10.1542/peds.2014-3407) and realized that the intestinal microbiome might be the culprit responsible for such an association.
The authors studied a population-based cohort of approximately 6 thousand boys and a similar number of girls in the first 24 months of life and looked at antibiotic purchase data as well as body mass index and height at 2 years of age. Since antibiotics can change the human microbiome, especially in infancy, doing so may trigger additional weight gain.
Why this happens is the subject of a provocative discussion section of this study, making this article well worth your attention.